Hanxi Xiao

Machine learning researcher building models for biological sequence data.
Hanxi Xiao

Hanxi (Han-Shee) Xiao

PhD Candidate
Joint CMU – University of Pittsburgh Program in Computational Biology
Das Lab · Center for Systems Immunology

I develop AI/ML methods for immunology, with a focus on statistical modeling and deep learning for noisy, high-dimensional biological signals. Currently, I am building an interpretable variant of attention mechanisms for transformer models.

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Selected Publications

  • SLIDE: Significant Latent Factor Interaction Discovery and Exploration across biological domains
    J Rahimikollu*, H Xiao*, et al — * equal contribution
    Nature Methods, 2024 Nature Methods
    Paper Research Briefing Pitt Coverage Cornell Coverage
  • Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD
    J Su*, H Xiao*, et al — * equal contribution
    JCI Insight, 2024 JCI Insight
    Paper
  • Spatial microniches of IL-2 combine with IL-10 to drive lung migratory TH2 cells in response to inhaled allergen
    K He, H Xiao, et al
    Nature Immunology, 2024 Nature Immunology
    Paper
  • From bench to bedside via bytes: Multi-omic immunoprofiling and integration using machine learning and network approaches
    H Xiao, et al
    Human Vaccines & Immunotherapeutics, 2023 Review
    Paper
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